Webof Tspan8 have been investigated in preclinical models. For example, the Isreco1 cell line derived from primary colorectal cancer (CRC) that does not express Tspan8 was … WebTSPAN8 has a small and a large extracellular loop that can mediate dimerization and association with other molecules including integrins, proteases, or cell signaling receptors. TSPAN8 is variably expressed on hematopoietic progenitor cells, spermatogonial stem cells, epithelial cells, and some tumor cells.
Mouse TSPAN8 Protein, His Tag (MALS verified)
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This gene is expres… WebThe TSPAN8 low cell population was enriched by multiple rounds of sorting and culture. The sgRNAs enriched in the TSPAN8 low cell population were identified by next-generation … the mory\\u0027s association new haven haven
National Center for Biotechnology Information
WebCD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophil, stimulated T lymphocytes and by neurons and glial cells in the peripheral nervous system. CD9 belongs to a family of membrane proteins termed tetraspanins which transverse the membrane four times. WebIntroduction. Non-small-cell lung carcinoma (NSCLC) is one of the leading causes of cancer-related mortality worldwide and accounts for about 85% of all lung cancers. 1,2 The most common types of NSCLC are squamous cell carcinoma, large cell carcinoma, and adenocarcinoma, but there are several other types that occur less frequently. 2 Aberrant … WebJan 29, 2024 · Tumor cell-derived extracellular vesicles (TEX) expressing tetraspanin Tspan8-alpha4/beta1 support angiogenesis. Tspan8-alpha6/beta4 facilitates lung … how to delete email trash folder