The SEMA3A gene is a member of the semaphorin family and encodes a protein with an Ig-like C2-type (immunoglobulin-like) domain, a PSI domain and a Sema domain. This secreted Semaphorin-3A protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, … See more Semaphorin-3A is a protein that in humans is encoded by the SEMA3A gene. See more The protein semaphorin-3A is highly expressed in scar tissue after traumatic central nervous system injuries, such as spinal cord injury. … See more • SEMA3A human gene location in the UCSC Genome Browser. • SEMA3A human gene details in the UCSC Genome Browser. See more • Schmidt EF, Strittmatter SM (2007). "The CRMP family of proteins and their role in Sema3A signaling". Semaphorins: Receptor and Intracellular Signaling Mechanisms. Adv. Exp. Med. Biol. … See more WebMar 16, 2007 · Semaphorin 则是一种轴突导向因子。 在神经系统发育过程中,神经元的轴突只有精确的抵达其目标位置才能形成具有正常生理功能的神经网络。 目前至少已经确认了4 …
Frontiers The Role of Semaphorins and Their Receptors in Innate
Web應用 [ 编辑] Lorem ipsum 從15世紀開始就被廣泛地使用在西方的 印刷 、設計領域中,在 電腦排版 盛行之後,這段被傳統印刷產業使用幾百年的無意義文字又再度流行。. 由於這段 … WebSemaphorin 3A (Sema3A; previously sem D, sema III or collapsin) is one of six Class 3 secreted semaphorins which share ~40-50% amino acid (aa) identity. (1-3). Class 3 semaphorins are potent chemorepellents that function in axon and/or vascular guidance during development (2, 3). The 772 aa mouse Sema3C contains a 20 aa signal sequence, … horse induction
Semaphorin 3A in the Immune System: Twenty Years of Study
WebApr 15, 2006 · Here, we show that semaphorin-3A (Sema-3A), a secreted member of the semaphorin family involved in axonal guidance, organogenesis, and angiogenesis, is highly expressed in several tumor cells. Conditioned media of Sema-3A-transfected COS-7 cells or human recombinant Sema-3A inhibited primary human T-cell proliferation and cytokines … Web以前,我们发现当人骨髓基质细胞在支持体内骨整合的钛基质上培养时,信号素 3A (sema3A) 的产生会增加,表明它可能会增强糖尿病患者的种植体周围成骨作用。在这里,我们建立了一个具有临床可移植性的自发发育的 T2DM 大鼠模型,并用它来评估 sema3A 的有 … WebNov 9, 1999 · Semaphorin 3A (Sema 3A; previously known as semaphorin III, semaphorin D, and collapsin-1), a secreted subtype of the semaphorin family, is an important axonal guidance molecule in vitro and in vivo. The … ps4 pad to pc