Nettetsubstrate of OCT1 Ligong Chen, Ph.D. Department of Pharmacology and Pharmaceutical Sciences School of Medicine April. 28th, 2015. Transporters Play Critical Roles in Drug and Nutrients A.D.M.E . ... Oct1 -/-ob/ob ** obesity mice ** OCT1 knockout mice showed less fat accumulation Nettet通过对IN690合金进行的固溶处理试验和压缩试验,研究了其合金晶粒组织和碳化物的变化规律以及碳化物对组织均匀性的影响.结果表明:晶粒组织随固溶温度的升高而增大,碳化物含量随温度升高而逐渐减小.当碳化物完全溶解时,晶粒会急剧长大.因而碳化物在晶界处有钉扎作用,限制晶粒的快速长大,对 ...
Recurrent Atherosclerotic Cardiovascular Disease Events …
NettetThe human organic cation transporter, OCT1 (SLC22A1), a member of the SLC22 family, was first cloned in 1997.1 Since then OCT1 has been characterized as a major drug … Nettet10. okt. 2016 · The resulting cellulose aerogels were characterized using various techniques. It was found that the CMC/CNF aerogel exhibited a honeycomb structure, and thus possessed anisotropic properties. Moreover, the fully biobased crosslinked organic aerogel possessed excellent mechanical properties based on both compression and … country french wall clock
OCT1 is a high-capacity thiamine transporter that regulates …
Nettet13. feb. 2024 · Oct1 (rabbit, Ab15112) antibody for Western blot (1:1000) and ChIP (1:50) was from Abcam (Cambridge, MA, USA). Rabbit IgG (sc-2027, 1:50), all of HRP-labeled secondary antibodies (1:4000), TSC2 (rabbit, sc-893, 1:1000), and β-actin (mouse, sc-47778, 1:2000) antibodies were from Santa Cruz Biotechnology (Santa Cruz, CA, USA). NettetLigong Chen1,2, Sook Wah Yee3, and Kathleen M Giacomini3,4,* 1Department of Pharmacology and Pharmaceutical Sciences, School of Medicine, Tsinghua University; ... Comment on: Chen L, et al.OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin. Proc Natl Acad SciUSA 2014; 111(27) ... NettetThe goal of this study is to identify genetic variants of OCT1 in Chinese and Japanese populations, which may potentially modulate response to metformin. We used recent data from the 1000 Genomes Project (Chinese and Japanese) and direct sequencing of selected amplicons of OCT1 in 66 DNA samples from Japanese patients with T2D. country french white desk